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Sofie helps life sciences teams work with conversations, files, meetings, documents, spreadsheets, and repeatable AI workflows in one place. Start with chat, then add the right context. Use a Workspace when Sofie needs shared files. Use CoDraft, CoMeeting, or CoSheet when the work becomes an artifact. Use Orchestrate when a workflow needs repeatable steps, review points, and reusable logic.

Start with the basics

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Quickstart

Set up your profile, start your first chat, and find your recent work.

Chat with Sofie

Learn the chat surface, model selector, voice input, history, and pinned chats.

Model selection

Choose a model, set a default, and understand speed, reasoning, and context tradeoffs.

How Sofie works

Learn how Sofie uses context, plans, capabilities, artifacts, and review points from chat.

Context windows

Understand context usage, long chats, summarized messages, and when to start fresh.

Tools and capabilities

Understand what Sofie can do from chat and how to ask for the right action.

Chat actions reference

Learn the actions Sofie can take from chat and the prompt patterns that steer them.

File Studio

Use file-based code sandbox work for Office files, generated files, and data transformations.

Chart and diagram generation

Create charts, diagrams, timelines, process maps, and visual summaries directly in chat.

Image Generation

Create or edit illustrations, infographics, icons, and visual concepts from chat.

Run work from chat

Move from a request to source search, artifact creation, workflow runs, and review.

Troubleshoot chat actions

Fix source, artifact, permission, and context issues when chat work goes off track.

Sources and search

Use attachments, Workspace search, Web search, Deep research, and citations.

Search Sofie

Find chats, Workspaces, CoDrafts, CoMeetings, CoSheets, Orchestrations, Sequences, and Templates.

Search results and filters

Filter, sort, and interpret Search results so you can reopen the right work.

Search versus chat sources

Choose between Search, Workspace search, Web search, Deep research, attachments, and selected context.

Plan Mode

Make Sofie propose, revise, and execute a structured plan for multi-step work.

Sofie Everywhere

Ask Sofie for help while viewing a CoDraft, CoSheet, CoMeeting, Workspace, or Orchestration.

Create artifacts from chat

Create, open, revise, import, export, and save durable Sofie work from chat.

Prompting patterns

Use practical prompt patterns for source review, drafting, data analysis, and workflows.

Confirmations and review

Control approvals, human input, artifact creation, connected app actions, and review points.

Conversation continuity

Continue work with chat history, pinned chats, plans, Saved prompts, Memory, and artifacts.

Workspaces

Organize files, teammates, chats, CoDrafts, CoMeetings, CoSheets, and Orchestrations.

Workspace knowledge

Centralize searchable source context so Sofie can answer from shared project knowledge.

Connected apps

Learn how Sofie can use enabled email, calendar, cloud file, and CRM sources.

Notifications

Track shared work, workflow updates, Sequence runs, meeting reminders, and account alerts.

Handoff and review

Return to paused work, inspect sources, and continue Sofie workflows from notifications.

Create and collaborate

CoDraft

Draft, revise, review, import, and export documents with Sofie and your team.

CoMeeting

Capture meetings, review transcripts, search past discussions, and share notes.

CoSheet

Analyze spreadsheets, write formulas from plain language, and collaborate on tables.

Templates

Create, fill, duplicate, pin, and manage reusable document structures.

Orchestrations

Build and run repeatable workflows with agents, tasks, tools, and human review.

Sequences

Schedule an Orchestration to run once or on a recurring cadence when enabled.

Use Orchestrations intelligently

Design reusable workflows with clear inputs, source rules, tests, review points, and publishing habits.

Structured Outputs

Define repeatable fields that improve agent handoff, artifact creation, and test validation.

Test Orchestrations

Create manual tests, save successful runs, validate outputs, inspect drift, and review run history.

Detailed task guides

Manage Workspace context

Upload files, organize folders, manage members, connect sources, and use Workspace search.

Format a CoDraft

Use tables, images, links, find and replace, review mode, revisions, and export.

CoDraft templates

Create reusable document templates and fill placeholders from chat or Orchestrations.

Manage Templates

Search, sort, preview, duplicate, pin, fill, and publish templates for recurring document work.

CoDraft review

Use comments, suggestions, review modes, and Sofie-assisted document review.

Capture a CoMeeting

Start capture, improve transcript quality, review notes, search meetings, and create follow-up work.

Use CoSheet formulas

Import data, write formulas, build pivot tables, create charts, and export to Excel.

Analyze CoSheet data

Use chat to profile data, find issues, suggest formulas, and summarize results.

Build with Sofie chat

Design, create, test, and refine an Orchestration from a chat conversation.

Structure task output

Use fields, groups, dropdowns, lists, and schema design patterns for reusable Orchestration outputs.

Test an Orchestration

Use realistic inputs, validation methods, run history, drift repair, Memory checks, and parallel-run checks.

Edit an Orchestration

Configure inputs, agents, tasks, output modes, review points, versions, and test runs.

Schedule a Sequence

Configure inputs, one-time or recurring schedules, test runs, notifications, and pause states.

Personalize Sofie

Saved prompts

Create, search, edit, and reuse prompt text for recurring chat requests.

Memory

Manage durable facts and preferences Sofie may use in future conversations.

Directives

Create standing rules for how Sofie should respond across conversations.

Memory review and cleanup

Review stale Memory, Directives, Episodes, Knowledge Graph, and Analytics views.

Account settings

Manage profile context, notification preferences, email signatures, and personal settings.

Profile and work preferences

Set role context, task interests, avatar, and password fields.

Security and passkeys

Add passkeys, understand required enrollment, and review account security options.

Notification preferences

Configure email, push, in-app, quiet hours, timezone, and notification types.

Email signatures

Create, preview, enable, and manage CoDraft email signatures.

Administration

Users, groups, and roles

Understand the access model across users, roles, groups, and Workspaces.

User management

Invite users, assign roles and groups, review details, and handle user removal.

Roles and permissions

Design roles, review permission impact, and manage privileged access.

Groups

Organize users by department, site, project, review board, or team.

Organization settings

Review organization settings, brand options, integrations, authentication policy, and Security Center.

Integration administration

Enable connected app providers and plan rollout for users.

Microsoft 365 setup

Configure Microsoft email, calendar, OneDrive, and SharePoint access.

Google Workspace setup

Configure Gmail, Google Calendar, and Google Drive access.

Salesforce setup

Configure Salesforce CRM and custom-object access.

Security Center

Review security events, alerts, access review snapshots, and recovery activity.

Life sciences workflows

Life sciences playbooks

Apply Sofie to tech transfer, CAPA, deviations, validation, URS, batch review, and quality risk workflows.
Review Sofie outputs before using them in regulated, quality, clinical, or controlled processes. Sofie can help you draft, analyze, and organize work, but your team owns final review and approval.